"The president emphasized the critical need to protect civilians and to separate the civilian population from Hamas including through corridors that allow people to move safely from defined areas of hostilities," according to a statement released by the White House.
The US has vigorously endorsed Israel's right to self-defense following the october 7 Hamas onslaught, in which israel claims 1,200 people were murdered and 138 remain captives.
However, the Biden administration claims that Israel's assaults are killing far too many Palestinian civilians. The dead toll had grown to 17,177 on thursday, according to the Hamas-run health ministry.
It has also advised israel, which is again targeting southern Gaza after a brief truce broke down last week, that the number of dead and displacements should not be as high as they were during the initial assault on the north.
On thursday, as fierce urban battle raged in and around Gaza's major towns, US Secretary of State Antony Blinken warned israel needed to do more.
"It remains critical that israel prioritise civilian protection," Blinken said on thursday during a press conference with visiting british Foreign Secretary David Cameron.
"There does remain a gap between... the intent to protect civilians and the actual results that we're seeing on the ground."
The US has also pushed for greater supplies to be delivered to Gaza.
Following the breakdown of a truce, Biden applauded Israel's move to allow additional gasoline in, "but stressed that much more assistance was urgently required across the board," according to the White House.
He also urged Hamas to provide the red Cross access to hostages held by the Palestinian terrorist group.
According to the White House, Biden talked separately with Jordan's king Abdullah II, as attempts to restore the brief truce that fell down last week continue.