In the year 2010, Vignesh karthik became famous as a contestant in 'Kalakka Povatu Yaaru' season 3 which was aired on Vijay TV. Following this, he also participated as a contestant in king of comedy Season 1 which started in 2011 on Vijay TV.
In 2016, he made his debut as a character actor in the film Nadpatikaram 79 on the silver screen based on his popularity through small screen shows. Later he acted in films like Sola Puri, Khurma Ahoya Ena, etc. Later, he took the avatar of the director with the film 'Enta Thalaiila Enna Vekala' which was released in the year 2018. The film, which was released on a different plot, was not a box office success, but was a critical success. Following this, he directed films like Project Two, Adiye. The recently released movie Adiye got a good response. Vignesh karthik, who marked himself as a successful film director with this film, got married yesterday, and now his wedding reception photos have been released. Many people including Vijay tv celebrities participated and congratulated the bride and groom. Photos of this are now going viral.