According to the results of an autopsy on the 54-year-old "Friends" star announced Friday, Matthew Perry died from the acute effects of the anesthetic ketamine. In the autopsy report, the Los Angeles County Department of Medical Examiner stated that Perry also drowned in "the heated end of his pool," but that it was a secondary role in his Oct. 28 death, which was ruled an accident.

According to the findings, coronary artery disease and buprenorphine, which is used to treat opioid use disorder, also played a role.

Perry was confirmed deceased after being discovered comatose at his home in Los Angeles' Pacific Palisades neighborhood. The autopsy was carried out the next day by investigators.

The actor had previously used narcotics but was "reportedly clean for 19 months," according to the article. According to the coroner, he was receiving ketamine infusion therapy to address depression and anxiety, and his last session was 1 1/2 weeks before his death.

According to the article, Perry had played pickleball earlier in the day, and his assistant, who lives with him, discovered him face down in the pool after returning from errands.

Perry had not been unwell, had made no health concerns, and had no signs of recent alcohol or drug use, according to the assistant.

Perry has been outspoken about his drug difficulties since his days on "Friends" in the 1990s.

"I loved everything about the show but I was struggling with my addictions which only added to my sense of shame," he writes in his autobiography published in 2022. "I had a secret and no one could know."


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