Menopause and Hormone Replacement Therapy (HRT)


Menopause brings physical and mental changes such as hot flashes, sleep disturbances, mood swings, and bone loss.


Hormone Replacement Therapy (HRT), using estrogen and progesterone, helps alleviate these symptoms.


Historical Concerns About HRT


In 2002, the Women's health Initiative (WHI) study claimed HRT increased risks of:


Heart disease

Breast cancer

Stroke


Result: Global fear of HRT; prescriptions dropped sharply.


Consequence: Millions of women suffered untreated menopausal symptoms and accelerated bone loss.

Updated Research and Benefits


Two decades of research show HRT is safer than previously thought.

Cardiovascular Health:


Starting HRT around age 50 does not increase heart risk.

May help maintain arterial elasticity.

Bone Health:


Estrogen slows bone loss, reducing osteoporosis and fracture risk.


Timely therapy strengthens bones as women age.


Cancer Risk:


Balanced estrogen-progesterone therapy may reduce breast cancer risk.


Why Initial Studies Were Misleading


Early studies did not adequately account for:

Age at therapy initiation

Hormone composition

Lifestyle factors

Biological variations


WHI report assumed universal risk, which modern research shows is incorrect.


Current Recommendations


HRT is safest and most effective when started near menopause onset (ages 45–55).


Modern data highlights benefits for:

Bone health

Heart health

Symptom management


Experts emphasize that outdated myths continue to unnecessarily scare women.


Global Impact


Following the WHI study, strict HRT restrictions were imposed in the US, Europe, and Asia.


In India, doctors avoided prescribing HRT for years, causing widespread discomfort among menopausal women.


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