A predictive modelling study has shown that giving a first dose of COVID-19 vaccine but delaying the second dose for people below the age of 65 could lead to fewer people dying of the disease. The study says that it will happen only if certain conditions are met.

As the pandemic goes wild day by day the debate whether to give the gap between doses or to follow the same gap that has been followed till now. For instance, Pfizer has said there is no clinical evidence to support Britain's decision to extend the gap between doses of its vaccine to 12 weeks, but data from the rollout in england shows protection against death of around 80% from one dose, with a 70% decline in infections.


A simulation model based on a ‘real-world’ sample of 100,000 US adults to find out potentially infectious interactions under different conditions. The studies included the tests on the efficacy and immunisation rates of the vaccine and varying assumptions as to whether the vaccine prevents transmission and serious symptoms or only prevents serious symptoms, including death.


Researchers, led by the Thomas C Kingsley of the Mayo Clinic in Rochester, Minnesota, said, "The results suggest that under specific conditions a decrease in cumulative mortality, infections, and hospital admissions can be achieved when the second vaccine dose is delayed."

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